Tridecapeptide-1

Bedst

Peptide

Tridecapeptide-1 at a glance

  • Helps improve the appearance of wrinkles
  • Can also visibly improve rough texture
  • Has benefits immediately and over time

Tridecapeptide-1 description

Tridecapeptide-1 is a synthetic patented peptide composed of a unique folded and encapsulated combination of the amino acids alanine, leucine, lysine, and valine. It has clinically proven wrinkle-smoothing action that produces visible results within 15 minutes of application. Over time, its line-smoothing benefits continue, leading to less visible wrinkles, including around the eyes and mouth. This targeted signal peptide works by influencing acetylcholine receptors within skin’s uppermost layers, helping to interrupt the process that leads to the appearance of expression lines. It also helps improve rough texture after four weeks of twice-daily use. Recommended usage levels of tridecapeptide-1 range from 1–10% in leave-on skin care products. Clinical data from the supplier has shown this ingredient’s efficacy is improved when paired with glycols used between 2–5%. *Note:* This ingredient’s name is one that’s known to be misused by disingenuous third-party suppliers looking to get their product into the marketplace sooner. Since Paula’s Choice uses this ingredient, we want to assure you that we’re purchasing direct from the originator of this peptide. Its ingredient name reflects the 13 amino acids present in the sequence, and the “-1” suffix simply differentiates it as the first International Nomenclature Cosmetic Ingredient (INCI) system registration of this name. The “=1” designation does not correlate to the amino acid sequence.

Tridecapeptide-1 references

  • The Journal of Clinical and Aesthetic Dermatology, May 2021, pages 14–21
  • Frontiers in Chemistry, October 2020, pages 1–10
  • Scientific Reports, January 2018, pages 1–11
  • Journal of Drugs in Dermatology, September 2016, pages 1,100–1,106

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Ratings af ingredienser

Bedst

Dokumenteret og understøttet af uafhængige studier. Fremragende aktiv ingrediens til de fleste hudtyper eller hudproblemer.

God

Nødvendigt for at forbedre en formulerings tekstur, stabilitet eller penetration.

Middel

Generelt ikke-irriterende, men kan have kosmetiske, stabilitetsmæssige eller andre problemer, der begrænser dets anvendelighed.

Dårlig

Der er risiko for irritation. Risikoen øges, når det kombineres med andre problematiske ingredienser.

Dårligst

Kan forårsage irritation, inflammation, tørhed osv. Kan være en fordel i nogle tilfælde, men generelt har man påvist, at ingrediensen gør mere skade end gavn.

Ukendt

Vi kunne ikke finde denne ingrediens i vores ingrediensordbog. Vi registrerer alle manglende ingredienser og foretager løbende opdateringer.

Ikke ratet

Vi har endnu ikke ratet denne ingrediens, fordi vi ikke har haft mulighed for at gennemgå forskningen om den.