Red 33 Lake God Colouring Agent/Pigment No known benefits Red 33 Lake at a glance Pigment used to add colour to makeup, food products, and skin care Also known as D&C Red No. 33 Aluminum Lake Ruled safe in its current use Red 33 Lake description Red 33 lake is a synthetic pigment used to add colour to makeup, as well as skin care and drugs. The term lake refers to the process of transforming a pigment from a solid to a solution, usually using a metallic salt. This makes it insoluble in water. Another name for this colorant is D&C Red No. 33 Aluminum Lake, with the “D&C” designation meaning it’s approved for use in drugs and cosmetics. The United States Food and Drug Administration has ruled Red 33 lake safe in its current use.